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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '626652b0a8439b6ef773f36738d1b88a0d7492f7484b0c7dcede4b377ec3ad7d' 
  AND token = '4ZaC4LNGOQs3Jwds34ioDVSMEKDxPHgSnIGdQMnuaCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}