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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8051acebf97b8db8c188a04465f4c2905e2cc734ae3fda54a4886cd4a4a1d0c' 
  AND token = 'JtAvhDspKqTxULGWOmy76n1XKN9KsfF6LCAzZ7nSdDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}