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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '030188e927a5dde51e6cde7ba47b24ddd659d9ed6b3322f6a2f2bbe02807a96c' 
  AND token = 'CSVzBCxpOB/1haEcJr7d+hng2Seb1ZJ1m+b6DMVLtsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}