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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1a49cdc6215268e7bc47f33449765b1f6dbb0fe89aa4b8f43668b46aa3cb31' 
  AND token = 'riRbW0SeKFGyG16gD+FVYF3PLQGWEPmMcugIz2ujeDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}