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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0428867f85011035c9960ec7565d34cef09d70131de8bf63b9b79ac7741c2f63' 
  AND token = 'lLUyTXDUjssFz+7ydE50G/8PTS10s+oWOMbCLxWoyJQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}