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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c0e2b734223e6cfbc3e3b7ec5556185439c261b359814c9d6da9f8d1e9d045' 
  AND token = 'q36YsvUrw+NyMqwldIZnQEIl4j0yxIZEN9lYmFqLC7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}