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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4db0e63186442d86d98ab58b54c86c5678ee20f13ec68eb5eefd1d06a7be69e5' 
  AND token = 'WcVm3s1zpByuTlbgFLb1rSQD6ngfr9aNHtmM7IdYpaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}