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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11c218eb68bf78d0c85a20a5396e60c03cff32a0d1478235e7eaaced18348396' 
  AND token = 'WPiWP2TG3woCqtCRBbn1tSe0HvVYU5a75lb5AMI49vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}