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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0025399fe0121c4b083a37f146886b1117b1d1b433d3a1990f11e71671f30f11' 
  AND token = 'LsryDzX+4ODzK8U3MWWxGO8wZkogvuszO+pL9yjNR7A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}