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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ae25606e4a1321346d9e9e2c9f785504a31777e49c2103b0866fc92203755a0' 
  AND token = '+xuNuSqfE5PnONqT0y0DoHmhBebrYHRw6jJsysvrYm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}