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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df712181603b05fcce3dae17e30d275f84927d3f6f1e5b25d8f35a2328c8e489' 
  AND token = 'NyHxNt+e2y2EkLAnQtoXuel2uv/KaLuRhhHdohb3dMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}