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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '549dc24fb6e20d29bab8ddd96f3e6b007aec940611270180a97bc0e8f624cf04' 
  AND token = '9kjVeIBnh5lxXkp4TzQvMKilCfZw7wFoSVRPKTc08/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}