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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97d49ceb1e707f165891342a7efe7fba05e5f50b19118da62091ff0e98350bb' 
  AND token = '/VR0WuV6uhgVpBBR8nTn1KgVgLUdF988RmZr1nNCWX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}