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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b05fd21397a789b8a91001524cf400b68bb14dc86718e6b6571d3bc4f130b83' 
  AND token = 'X0tsgN0gsoqWPh4YlnFWLX5dO3855uhsh5qGTkgYhI8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}