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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54d1b5243bb82e92825b704ec3b809da6c0489ba8f994298603e59a7fb67d3d4' 
  AND token = 'oiUdRgnz5QA9tzQGSvWPBvNbdBCuLIqf9rL0Ec4fZMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}