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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c7a0a94e4e7859132c363c36fc2e9f280a249cad22872bf1a242e7f55c8841d' 
  AND token = 'H8vcJ2/5gWlZeoEJ7NgQYiOk5PXlknk0JRXZIiDyPe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}