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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d9b7330a5bd11502647ae5bfb08c6c17fde736ddccd78a8711a8c6e12daa7a1' 
  AND token = 'S+ll6Rw4/07s1BCE4ZlOkEpP45XdHB34B1xj9Dw1stQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}