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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e186faebea5c7de188dccd3b40dcb623d70b3a48e44a98da461a4bdea8fa9ada' 
  AND token = 'LOAB1Dqrc0/GbGxsV3hrsLg/6KbvfomT1w9A2nha7d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}