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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40c2aad2f427e831dad06eacdd421a9db45414bd28a99d341a14216407505b8e' 
  AND token = 'pZUUbA1zhx03uQSdgTVKpYAYcVnUTeT6omFCH1ad7yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}