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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'faf146f58fb64ad7f7edd69b7d9396b117e974b99e7c3dab22f189253ddab9f8' 
  AND token = 'Z1P4yAmljb4nNKU0H+M6jbdjcfkesTBSM5ZOg9L+qjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}