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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '894404fd5deffc43179a1b9061decba2abb2c7bd0cb9b92ee7cd01100d5046c6' 
  AND token = 'zZtaL/NLygGia+TqpVx6mwZAwE6jIcQQ8UPS04Hp9to=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}