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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9257181caa40e68180e4f566be95b205a48f8e8c49297e06d77f5e5063d5e25e' 
  AND token = 'EhCXByaFp37ip46Pc+YLGVj1vynOxXyXJNbGV0ZKeAE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}