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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f01ccfd51376a27598f191da2eddb1e5745b0906e4375be37b2c7c8a19693493' 
  AND token = 'WVicKFSL9nbLHkGp9wDXciTIL1PM2Fi7sRJTso1uzFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}