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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d41a243db3090adee34b75b4b17cd5a805fd120854e7b98e39cecbffd71af1e' 
  AND token = 'NGl58kAPbXeIEyxqi75PY9oCaMCM7NZxUumJfetQ57o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}