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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bd3c4786760040c4072badce736747877809acd152192ebd6bbf32a81036595' 
  AND token = 'ekWCc1Wah7EWxsPL/JA80CxeCGNfe91kQgatAyya3AU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}