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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c52305d4a54cad2202990fb1ebd4ef6f3afabbfa229520edd59a9d75146ae4b5' 
  AND token = 'iFY/dNhZyu7CHx1XYk0loC8y22PY+xzMSwoT23V5jMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}