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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c3a422c74768026931a2299720c657d664d9cbadccc6c691966d5dad2809e2e' 
  AND token = 'VNk7l4IhmlFdg82p+U6MICibmb+xhalY9g+6tMYRK+g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}