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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe2143b6d95d789d98cbfc6f574ed8c9d5fb4ee1f2e5e3ad9723a6e0e3a6d7d0' 
  AND token = 'a+12U/VBVCdmDB3jkNFlQ0YEG7G9AB0oVNsYtqWQQJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}