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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d05f7b8af9c2e6392c9ddc36b1c7e35322d2466c37b7832d320ac957abf1d93' 
  AND token = '+6+EWBWqU/bTc/+roUp3toaFLurbY0Zci+7+ZLjJGgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}