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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b0ffbfbbaeb4bf9d5b640bf8ed24d74aafd8539c936d4932b510771acda8a95' 
  AND token = 'Zh43ES4ITG2YeKkHC/zaJM9UZG/nyeBWnqaiKqOsrL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}