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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27d8972e411955e1664d39fa783662a85997a8450e356da5bc11cad0e45dd5f6' 
  AND token = 'N2ln8B68LGsX+9nhRg7eyUCFj9lnuqEzu13/vo2xhG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}