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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46653e96052f318e50d94e05cffdb9064a75b4ea1d5fb3755377b907094b4327' 
  AND token = 'DRgLifgcNvFCfaT6YxURp2KJmNQfJAVFzjq0HIofQIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}