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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e9f745851c63935cb10cac1343934d44309703387535164054bd4448836365' 
  AND token = '7kfktgOll1VOf/CT2Sk+B/aAy/QIPsWbV7aT/r5bWjI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}