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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dbca05171a548a87e034bc06c58e8940232109c40dbe8a5295ee252c829068d' 
  AND token = 'JX9sl2ly9MNQ4G5nshbiC23sZBSEpGcWbU29DnOE3Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}