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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df4b4c11cb07e01311c988bee0f6727d1a518039ddc07e422c4862eda6c239ee' 
  AND token = '1UUhCOqswKGfglQcoq3LAzOSt6B2h/s8cFqAPd5dWi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}