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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0a4735404ac9a490f5000bfe517ab5b8c864965a3d41376c3019d78209b8cd0' 
  AND token = 'tvKyA4fN7Vl3rv+nbt2+vFyGhSTD7bNcmzXrlKZHhBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}