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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b0cf0281f1c4df973022d3966b94de047bb362f1ef5ff3e486a78ba4e7f11c72' 
  AND token = '34CkRC1KhhkYTUR59kOKTxuNILfj0jsHGzIiO5FOlh0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}