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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '324d4cc880366559b902255e446b3c0984cf2bac588f753e9b15a68223330707' 
  AND token = 'gjH8ey5UqlI/k5jMCjylhlyDPoWfhm84EDwR6Z7pw+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}