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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc1a9894a02202c49a86066575e9e7474160d01b4d0ee19a40bf7af395dff2d8' 
  AND token = 'FNmu3uN+bPZGZuC5sGyErNo2ghJzX1Kz0gxaaagNFEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}