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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9ff5d451de493fe02c86efe0eb6cd08e0fe82c567c63543bea45d02a60dde30b' 
  AND token = 'M6pRhSsFV9snE4y0KpGK7QpHBW8qZYZt/mQ7e2d+YqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}