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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a21404210cd4c22c70ba2ad15cbf51099b3451e42b2f2e59784254c3b37ed97' 
  AND token = 'KFA26K/lruxIkZ1p5wPQvdzdKEecUNY9Jjg8E7IizR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}