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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01133716b16d9b1c1dfc7d9ffb2a019d566e4dafe1b67a111d5f111359b765f0' 
  AND token = 'CSzjrhXNFDenZpNdW+Zu9hoGupnf36ZczMnZLMn9HMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}