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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61b4844a594e5ca6dd5833c3e8d8d3be75b29a29f683fe6a2cbdd02e3c734e72' 
  AND token = 'yyw2nxKF8Uz+fwFkz7BEAQETaAGwmNFeXv/BWWH998c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}