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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '776df65d65f4759bec2689ba50535956b0eeca1cdcb9b16b2f8fe44336fbae40' 
  AND token = 'TFoAaSJqxvx0OkhUMVNd3NBpK3Uii/OnfyPeN3liDGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}