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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '68e42986f74026fea81171b64e2910fa272313cf971173072de42f2a92a60f64' 
  AND token = 'ZDN1xkhwS3t/IdYvRGWf6d7kNGpQDzuA4Z46fvTarL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}