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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c58c30133812a87b490ef2ad1d11a9d5ad7d276233e8813dc8923a5b615303e1' 
  AND token = 'vLsoTgz6IKQ8U6G21aFohoMLVoyMwEuUqQItsobbg+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}