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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '017d6a6671bf34b92788e38376cf3096d2466aaa5602dd719c9816f5866e0786' 
  AND token = 'O426jU3yZD/VOUHdgB5XPnPrgKXLf2ZokR4DmqL9kGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}