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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '275abe4a5512f3526ee93b559364b25f238de57952d3d0ef282d4e9fd6f1e427' 
  AND token = 'quV/pBetOF+XIHsDPihTnMLhnDVpLAy/3AQu0XnTJVc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}