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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2bde53c4c03cb0aac2f328a334f3df0026004adcb9d462ea89523236a8533f5' 
  AND token = '4MGINPS+zNM+VKaqFR+FnO0DiamlzMmtZpHQcQ2YcG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}