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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eeed63d85412da862a8650f41b524138d08cac5d4be9376c13ac5418d21801f' 
  AND token = 'HTFhOIfg5u+exFdAdQUS4eBrD93ONMCO/EsGLR9RNL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}